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Xeomin®: What is it and How
Xeomin® Compares to BOTOX®
Xeomin® (incobotulinumtoxinA),
made by Merz Pharmaceuticals, is approved by the US FDA for the treatment of
adults with cervical dystonia or blepharospasm and Moderate to severe frown
lines between the eyebrows. IncobotulinumtoxinA
is made from the bacteria that causes botulism. Botulinum toxin blocks nerve
activity in the muscles, causing a temporary reduction in muscle activity.
FDA approval of XEOMIN®, was based on the results of two U.S. clinical
trials. A study cited in the Journal of Neurological Sciences on the efficacy
and safety of XEOMIN® found it showed “non-inferiority” to Botox® when used in
the same doses to treat cervical dystonia. It concluded that XEOMIN® is a safe
and effective treatment for the disorder.
Xeomin® has now been approved for
some cosmetic indications – Moderate to severe frown lines between the
eyebrows. Similar to other drugs in this category, including Botox® and
Dysport®, that also have FDA approval for the treatment of facial wrinkles. Now
that Xeomin® is available and FDA approved, doctors can use it both on-label
and off-label to treat the same facial lines treated by Botox® and Dysport®,
including frown lines, crow’s feet and forehead wrinkles.
Worldwide, more than 84,000
people have been treated with Xeomin® injections. The U.S. is actually the 20th
country to approve this new drug. It is available in 50-unit and 100-unit
vials.
Better or worse than Botox®?
Xeomin® is the first one that
does not need to be refrigerated before use, which may simplify distribution.
Xeomin® is also has no additives, just botulinum toxin type A. This may mean
that there is less risk of developing antibodies against Xeomin® than other
available neurotoxins. The body develops antibodies in response to a foreign
invader and attacks. In theory, antibodies could prevent a neurotoxin from
having its desired effects. The effects of Xeomin® occur within one week, and
the results last from three to six months, making it comparable to Botox in
terms of both onset and duration of action. Xeomin® should not be used
interchangeably with other botulinum products.
What are the risks?
There is a risk that all
botulinum toxin products may spread from the area where they were injected to
other parts of the body, causing potentially life-threatening swallowing and
breathing problems. This was predominantly seen in children treated with Botox
off-label for cerebral palsy. These issues have not been reported among people
who received botulinum products for cosmetic uses or to treat blepharospasm.
Other risks may include bleeding
and bruising at the injection site and allergic reactions such as itching,
swelling or shortness of breath. Your doctor should discuss all the potential
risks of this procedure with you during your consultation.
When Xeomin® is used to treat
cervical dystonia, side effects include neck pain, muscle weakness, injection
site pain and musculoskeletal pain. When used to treat blepharospasm, the most
common side effects of Xeomin® were eyelid sagging, dry eye, dry mouth,
diarrhea, headache, visual impairment, shortness of breath (dyspnea), and upper
respiratory infections.
How much does Xeomin® cost?
Xeomin® costs will likely be
comparable to Botox® if not slightly lower. Exact price points are not yet
available since Xeomin® was so recently approved for use in the U.S. If your
doctor suggests Xeomin®, make sure to get accurate pricing information before
booking your appointment.
Buy Xeomin online in USA , CA, AU
and EUROPE
https://www.acquafiller.com/xeonin-botulinum-toxin-type-a-100u